[maker-devel] Question about AED scores

[Daniel Standage]

Good morning!

I have a quick question or two about the AED scores reported for each
transcript annotated by Maker. So, if I understand correctly, AED is 1-C,
where the congruency C is the average of the sensitivity and specificity.
The sn and sp values can be calculated for different levels (whole
transcripts, exons, or individual nucleotides), but the text of the Maker2
paper suggests the reported AED value is calculated based on
nucleotide-level congruency with the aligned evidence--is this correct?

I'm assuming this score is stored in the *_AED* attribute, which leads to
my other question: what does the value of the *_eAED* attribute represent?
Is this the same score calculated at the exon level?

Many thanks!

--
Daniel S. Standage
Ph.D. Candidate
Bioinformatics and Computational Biology Program
Department of Genetics, Development, and Cell Biology
Iowa State University
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