[maker-devel] About eAED

[Carson Holt]

eAED is an extended AED calculation that does some inference about the evidence (i.e. checks reading frame and not just overlap, and may infer support for an exon if by splice sites are confirmed etc.). If eAED is 1 that means that while there is evidence supporting the model, the evidence is more likely to be spurious, so it may be a false model.

—Carson

 
> On Oct 4, 2017, at 4:31 PM, Quanwei Zhang <qwzhang0601 at gmail.com> wrote:
> 
> Hello:
> 
> I ran the maker2 pipeline and got the default gene sets (with AED<1). But I found there are several hundred genes with eAED 1. 
> 
> Below is an example, the gene has AED 0.05 and eAED 1. I wonder what can be the reason of the great difference between AED and eAED. For this gene it has a very low AED score, is it still a reliable gene model if its eAED equals 1?  
> 
> >maker-Contig2656-snap-gene-269.6-mRNA-1 protein AED:0.05 eAED:1.00 QI:75|0|0|1|0|0|2|111|35
> 
> Thanks
> 
> Best
> Quanwei
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