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MAKER is a portable and easily configurable genome annotation pipeline. Its purpose is to allow smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to a genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MAKER is also easily trainable: outputs of preliminary runs can be used to automatically retrain its gene prediction algorithm, producing higher quality gene-models on seusequent runs. MAKER's inputs are minimal and its ouputs can be directly loaded into a GMOD database. They can also be viewed in the Apollo genome browser; this feature of MAKER provides an easy means to annotate, view and edit individual contigs and BACs without the overhead of a database. MAKER should prove especially useful for emerging model organism projects with minimal bioinformatics expertise and computer resources.
To download the current MAKER distribution for academic research use we ask you to register with a valid e-mail address. We are asking for this information so that we can keep track of new users for generating usage reports for funding agencies. Your e-mail address will be used for creating an anonymous aggregate count of MAKER users and will not by used for any other purposes. Your e-mail will not be shared or made public in any way and we won't even subscribe you to our mailing list - you can do that seperately.
To download MAKER for academic research use or to access an existing academic or commercial license, please visit our Registration Page.
MAKER Web Annotation Service
MAKER supports a web based interface, and a version of MAKER has been installed online that users can try via a web browser. The MAKER Web Annotation Service (MWAS) can be accessed using the link below. Please be aware that job submission size is limited, so if you need to run large jobs, you will want to install MAKER locally.
Documentation for the MAKER project can be found included in the MAKER distribution, and is included on this website as well with links below.
Support for MAKER is provided by a mailing list. Please join the mailing list and become a member of the MKAER community.
Subscribe/Unsubscribe to the maker-devel mailing list.
Send mail to the maker-devel list (members only - sign up above).
The maker-devel list is also archived on Google Groups which has better archive searching capabilities.
Having fun with MAKER? Proudly sport your new annotation addiction with some MAKER bling!